Research Publication
Chemistry Professor Aaron Leconte
Assistant Professor of Chemistry Aaron Leconte is co-first author on an article published in the journal Biochemistry (link: The article, "A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes" was written in conjunction with Bryan Dickinson, David Yang, Irene Chen, Ben Allen and David R. Liu in the Department of Chemistry and Chemical Biology at Harvard University. The work describes the development and application of a new method for studying how a protein evolves over long time periods. The authors used this new model system to test the repeatability of evolution; the authors found that evolution is highly repeatable, but very sensitive to the conditions of the experiment. The new model system is expected to contribute to our understanding of protein evolution, which has wide-ranging impacts in diverse areas ranging from human disease to the origin of life itself.  


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